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| Registros recuperados : 16 | |
| 1. |  | NEVES, C. J.; FERREIRA, G. B.; FERNANDES, H. D.; GADINNI, C.; MATOS, R. S. Estimativas de parametros geneticos para producao de leite e gordura em bovinos da raca holandesa no estado de Goias. In: REUNIAO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 35., 1998, Botucatu, SP. Anais... Botucatu: SBZ, 1998. v.3. p.529-231.| Biblioteca(s): Embrapa Cerrados. |
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| 4. | | SOUSA, G. A.; SANTOS, I. B.; KAPRITCHKOFF, R. T. I.; SANTOS, L. A. L.; MINHO, A. P.; MATOS, R. S.; CHAGAS, A. C. de S. Amblyomma sculptum e Rhipicephalus microplus: estudo comparativo da eficácia de antiparasitários in vitro e no semicampo. In: CONGRESSO BRASILEIRO DE PARASITOLOGIA VETERINÁRIA, 21., Ilhéus, 2022. Ilhéus: CBPV, 2023. p. 358.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 5. | | KAPRITCHKOFF, R. T. I.; SANTOS, L. A. L. DOS; VARQUEZ, V. C.; ANHOLETO, L. A.; MATOS, R. S.; OKINO, C. H.; CHAGAS, A. C. de S. Determinação da frequência de haplótipos da B-globina ovina e comparação com características fenotípicas em ovinos das raças Santa Inês, Texel e White Dorper submetidos à infecção natural por Haemonchus contortus. In: JORNADA CIENTÍFICA DA EMBRAPA SÃO CARLOS, 14., 2022, São Carlos, SP. Anais... São Carlos, SP: Embrapa Instrumentação; Embrapa Pecuária Sudeste, 2022. p. 65. (Embrapa Instrumentação. Documentos, 73).| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 6. | | MATOS, R. S.; BARROSO, P. M.; SENRA, L.; KAPRITCHKOFF, R. T. I.; MONTEIRO, C. M. O.; PRATA, M. C. de A.; MATURANO, R.; CHAGAS, A. C. de S. Sensibilidade a carrapaticidas em populações de Rhipicephalusmicroplus da região sudeste do país. In: CONGRESSO BRASILEIRO DE PARASITOLOGIA VETERINÁRIA, 21., 2022, Ilhéus. Antigos problemas, novos paradigmas: resumos. Ilhéus: Sociedade Brasileira de Parasitologia Veterinária, 2022. p. 526.| Biblioteca(s): Embrapa Gado de Leite; Embrapa Pecuária Sudeste. |
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| 7. | | ARAÚJO, L. X.; NOVATO, T. P. L.; ZERINGOTA, V.; MATOS, R. S.; SENRA, T. O. S.; MATURANO, R.; PRATA, M. C. de A.; DAEMON, E.; MONTEIRO, C. M. O. Acaricidal activity of thymol against larvae of Rhipicephalus microplus (Acari: Ixodidae) under semi-natural conditions. Parasitology Research, v. 114, n. 9, p. 3271-3276, 2015.| Biblioteca(s): Embrapa Gado de Leite. |
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| 8. | | SILVA, M. M. C. da; RODRIGUES, M. T.; SILVA, M. T. C. da; MAGALHÃES, A. C. M. de; RODRIGUES, C. A. F.; BRANCO, R. H.; MATOS, R. S.; SILVEIRA, T. S. Perfil de ácidos graxos do leite de cabra recebendo suplementos de lipidios na dieta. In: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 43., 2006, João Pessoa. Produção animal em biomas tropicais: anais dos simpósios. João Pessoa: Sociedade Brasileira de Zootecnia, 2006. 4 f.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 9. | | KAPRITCHKOFF, R. T. I.; OKINO, C. H.; MATOS, R. S.; BELLO, H. J. S.; MELITO, G. R.; DONATONI, F. A. B.; NICIURA, S. C. M.; CHAGAS, A. C. de S. Efeito do polimorfismo da β-globina na anemia por Hemoncose em ovinos de diferentes raças. In: CONGRESSO PAULISTA DE PARASITOLOGIA, 10., Jaboticabal, 2023. Jaboticabal: Sociedade Paulista de Parasitologia, 2023.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 10. | | BELLO, H. J. S.; SANTOS, J. DE C.; KAPRITCHKOFF, R. T. I.; FIORENTINO, M. I. M.; MELITO, G. R.; DONATONI, F. A. B.; NICIURA, S. C. M.; ESTEVES, S. N.; MATOS, R. S.; CHAGAS, A. C. de S. Influência da substituição parasitária de Haemonchus contortus no ganho de peso de cordeiros. In: CONGRESSO PAULISTA DE PARASITOLOGIA, 10., Jaboticabal, 2023. Jaboticabal: Sociedade Paulista de Parasitologia, 2023.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 11. | | KAPRITCHKOFF, R. T. I.; OKINO, C. H.; NICIURA, S. C. M.; BELLO, H. J. S.; MATOS, R. S.; MELITO, G. R.; DONATONI, F. A. B.; ESTEVES, S. N.; CHAGAS, A. C. de S. Association of β-globin polymorphisms and tolerance to haemonchosis in ewes and lambs of different sheep breeds. Veterinary Parasitology, v. 328, june 2024, 110163. 8 p.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 12. | | BELLO, H. J. S.; SANTOS, J. DE C.; KAPRITCHKOFF, R. T. I.; FIORENTINO, M. I. M.; MELITO, G. R.; DONATONI, F. A. B.; NICIURA, S. C. M.; ESTEVES, S. N.; MATOS, R. S.; CHAGAS, A. C. de S. Avaliação do OPG e frequência de tratamentos com anti-helmínticos em cordeiros submetidos à substituição parasitária de Haemonchus contortus. In: CONGRESSO PAULISTA DE PARASITOLOGIA, 10., Jaboticabal, 2023. Jaboticabal: Sociedade Paulista de Parasitologia, 2023.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 13. | | BELLO, H. J. S.; KAPRITCHKOFF, R. T. I.; MELITO, G. R.; FIORENTINO, M. I. M.; SANTOS, J. de C.; DONATONI, F. A. B.; MATOS, R. S.; ESTEVES, S. N.; CHAGAS, A. C. de S. Eficácia do tratamento anti-helmíntico em ovinos após substituição parasitária com isolado suscetível Haemonchus contortus. In: JORNADA CIENTÍFICA DA EMBRAPA SÃO CARLOS, 15., 2023, São Carlos, SP. Anais [...]. São Carlos, SP: Embrapa Pecuária Sudeste; Embrapa Instrumentação, 2023. p. 27. (Embrapa Pecuária Sudeste. Eventos Técnicos & Científicos, 1)| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 14. | | FILGUEIRAS, M. D. G.; MATOS, R. S.; BARRETO, L. P.; MASCARIN, G. M.; RIZZO, P. V.; FREITAS, F. M. C.; PRATA, M. C. de A.; MONTEIRO, C.; FERNANDES, E. K. K. From the laboratory to the field: efficacy of entomopathogenic nematodes to control the cattle tick. Pest Management Science, v. 79, n. 1, p. 216-225, 2022.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 15. | | FILGUEIRAS, M. D. G.; MATOS, R. S.; BARRETO, L. P.; MASCARIN, G. M.; RIZZO, P. V.; FREITAS, F. M. C.; PRATA, M. C. de A.; MONTEIRO, C.; FERNANDES, E. K. K. From the laboratory to the field: efficacy of entomopathogenic nematodes to control the cattle tick. Pest Management Science, v. 79, n. 1, p. 216-225, 2023.| Biblioteca(s): Embrapa Gado de Leite. |
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| 16. | | ROCHA, A. L. F.; NUNES, R. Z. de A.; MATOS, R. S.; FONSECA FILHO, H. D. da; BEZERRA, J. de A.; LIMA, A. R.; GUIMARÃES, F. E. G.; PAMPLONA, A. M. S. R.; MAJOLO, C.; SOUZA, M. G. de; CAMPELO, P. H.; TÃLU, s.; BAGNATO, V. S.; INADA, N. M.; SANCHES, E. A. Alternative controlling agent of Theobroma grandiflorum pests: nanoscale surface and fractal analysis of gelatin/PCL loaded particles containing Lippia origanoides essential oil. Nanomaterials, v. 12, n. 15, art. 2712, 2022.| Biblioteca(s): Embrapa Amazônia Ocidental. |
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| Registros recuperados : 16 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
21/03/2024 |
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Data da última atualização: |
22/03/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
KAPRITCHKOFF, R. T. I.; OKINO, C. H.; NICIURA, S. C. M.; BELLO, H. J. S.; MATOS, R. S.; MELITO, G. R.; DONATONI, F. A. B.; ESTEVES, S. N.; CHAGAS, A. C. de S. |
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Afiliação: |
RAFAELA TAMI IKEDA KAPRITCHKOFF, Universidade Estadual Paulista; CINTIA HIROMI OKINO, CPPSE; SIMONE CRISTINA MEO NICIURA, CPPSE; HORNBLENDA JOAQUINA SILVA BELLO; RENATA SILVA MATOS; GLAUCIA ROBERTA MELITO; FLAVIA ALINE BRESSANI DONATONI, CPPSE; SERGIO NOVITA ESTEVES, CPPSE; ANA CAROLINA DE SOUZA CHAGAS, CPPSE. |
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Título: |
Association of β-globin polymorphisms and tolerance to haemonchosis in ewes and lambs of different sheep breeds. |
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Ano de publicação: |
2024 |
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Fonte/Imprenta: |
Veterinary Parasitology, v. 328, june 2024, 110163. |
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Páginas: |
8 p. |
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DOI: |
10.1016/j.vetpar.2024.110163 |
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Idioma: |
Inglês |
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Conteúdo: |
Gastrointestinal nematodes (GIN), especially Haemonchus contortus, represent a significant challenge for sheep production. Given the global concern about GIN anthelmintic resistance, alternative control methods able to reduce the dependence on these drugs are highly advisable. Since previous studies have shown that sheep carrying the Hb-A allele of β-globin are more resistant to H. contortus, this study aimed to investigate the relationship between the different haplotypes (Hb-AA, Hb-AB and Hb-BB) and phenotypes in Santa Inês (SI), Texel (TX) and White Dorper (DO) breeds infected with H. contortus. Blood samples were collected from 180 ewes and 123 lambs of the three breeds for DNA extraction followed by qPCR using a hydrolysis probe to identify the β-globin haplotypes. Phenotypic data, including fecal egg count (FEC), packed cell volume (PCV), FAMACHA score and body condition score for ewes and lambs, as well as weight gain for lambs, were collected. The genotypic frequencies of β-globin for ewes and lambs were, respectively: 21.7% and 21.4% Hb-AA, 50% and 50% Hb-AB and 28.3% and 28.6% Hb-BB in SI; 0% and 0% Hb-AA, 18.6% and 9.4% Hb-AB and 81.4% and 90.6% Hb-BB in TX; and 0% and 0% Hb-AA, 13.1% and 0% Hb-AB and 86.9% and 100% Hb-BB in DO. In ewes, mean PCV differed (p<0.05) between the three haplotypes, with higher PCV in Hb-AA animals, followed by Hb-AB and Hb-BB. When considering each breed separately, SI Hb-AA ewes presented higher PCV (p<0.05), highlighting that even in a breed already considered resistant, animals with Hb-AA haplotype showed superior performance. Lambs with the Hb-AA haplotype exhibited a higher (p<0.05) mean PCV compared to those with Hb-AB and Hb-BB. The same pattern was found in SI when analyzing each breed separately. No significant association was found between β-globin haplotypes and FEC, FAMACHA score, body condition score, or weight gain. Nevertheless, given that anemia is the major clinical sign of haemonchosis, our findings on PCV reinforce that sheep carrying the Hb-A allele of β-globin are more tolerant to haemonchosis. This study may support the development of a valuable tool, targeting genetic selection for GIN control, reducing the dependence on anthelmintics and boosting sheep production worldwide. MenosGastrointestinal nematodes (GIN), especially Haemonchus contortus, represent a significant challenge for sheep production. Given the global concern about GIN anthelmintic resistance, alternative control methods able to reduce the dependence on these drugs are highly advisable. Since previous studies have shown that sheep carrying the Hb-A allele of β-globin are more resistant to H. contortus, this study aimed to investigate the relationship between the different haplotypes (Hb-AA, Hb-AB and Hb-BB) and phenotypes in Santa Inês (SI), Texel (TX) and White Dorper (DO) breeds infected with H. contortus. Blood samples were collected from 180 ewes and 123 lambs of the three breeds for DNA extraction followed by qPCR using a hydrolysis probe to identify the β-globin haplotypes. Phenotypic data, including fecal egg count (FEC), packed cell volume (PCV), FAMACHA score and body condition score for ewes and lambs, as well as weight gain for lambs, were collected. The genotypic frequencies of β-globin for ewes and lambs were, respectively: 21.7% and 21.4% Hb-AA, 50% and 50% Hb-AB and 28.3% and 28.6% Hb-BB in SI; 0% and 0% Hb-AA, 18.6% and 9.4% Hb-AB and 81.4% and 90.6% Hb-BB in TX; and 0% and 0% Hb-AA, 13.1% and 0% Hb-AB and 86.9% and 100% Hb-BB in DO. In ewes, mean PCV differed (p<0.05) between the three haplotypes, with higher PCV in Hb-AA animals, followed by Hb-AB and Hb-BB. When considering each breed separately, SI Hb-AA ewes presented higher PCV (p<0.05), highlighting that even in... Mostrar Tudo |
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Palavras-Chave: |
Ovine; Parasite tolerance; Resilience. |
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Thesagro: |
Anemia; Haemonchus Contortus. |
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Thesaurus NAL: |
Genotyping; Haplotypes. |
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Categoria do assunto: |
H Saúde e Patologia |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/263903/1/AssociationBGlobin.pdf
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Marc: |
LEADER 03233naa a2200325 a 4500
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008 2024 bl uuuu u00u1 u #d
024 7 $a10.1016/j.vetpar.2024.110163$2DOI
100 1 $aKAPRITCHKOFF, R. T. I.
245 $aAssociation of β-globin polymorphisms and tolerance to haemonchosis in ewes and lambs of different sheep breeds.$h[electronic resource]
260 $c2024
300 $a8 p.
520 $aGastrointestinal nematodes (GIN), especially Haemonchus contortus, represent a significant challenge for sheep production. Given the global concern about GIN anthelmintic resistance, alternative control methods able to reduce the dependence on these drugs are highly advisable. Since previous studies have shown that sheep carrying the Hb-A allele of β-globin are more resistant to H. contortus, this study aimed to investigate the relationship between the different haplotypes (Hb-AA, Hb-AB and Hb-BB) and phenotypes in Santa Inês (SI), Texel (TX) and White Dorper (DO) breeds infected with H. contortus. Blood samples were collected from 180 ewes and 123 lambs of the three breeds for DNA extraction followed by qPCR using a hydrolysis probe to identify the β-globin haplotypes. Phenotypic data, including fecal egg count (FEC), packed cell volume (PCV), FAMACHA score and body condition score for ewes and lambs, as well as weight gain for lambs, were collected. The genotypic frequencies of β-globin for ewes and lambs were, respectively: 21.7% and 21.4% Hb-AA, 50% and 50% Hb-AB and 28.3% and 28.6% Hb-BB in SI; 0% and 0% Hb-AA, 18.6% and 9.4% Hb-AB and 81.4% and 90.6% Hb-BB in TX; and 0% and 0% Hb-AA, 13.1% and 0% Hb-AB and 86.9% and 100% Hb-BB in DO. In ewes, mean PCV differed (p<0.05) between the three haplotypes, with higher PCV in Hb-AA animals, followed by Hb-AB and Hb-BB. When considering each breed separately, SI Hb-AA ewes presented higher PCV (p<0.05), highlighting that even in a breed already considered resistant, animals with Hb-AA haplotype showed superior performance. Lambs with the Hb-AA haplotype exhibited a higher (p<0.05) mean PCV compared to those with Hb-AB and Hb-BB. The same pattern was found in SI when analyzing each breed separately. No significant association was found between β-globin haplotypes and FEC, FAMACHA score, body condition score, or weight gain. Nevertheless, given that anemia is the major clinical sign of haemonchosis, our findings on PCV reinforce that sheep carrying the Hb-A allele of β-globin are more tolerant to haemonchosis. This study may support the development of a valuable tool, targeting genetic selection for GIN control, reducing the dependence on anthelmintics and boosting sheep production worldwide.
650 $aGenotyping
650 $aHaplotypes
650 $aAnemia
650 $aHaemonchus Contortus
653 $aOvine
653 $aParasite tolerance
653 $aResilience
700 1 $aOKINO, C. H.
700 1 $aNICIURA, S. C. M.
700 1 $aBELLO, H. J. S.
700 1 $aMATOS, R. S.
700 1 $aMELITO, G. R.
700 1 $aDONATONI, F. A. B.
700 1 $aESTEVES, S. N.
700 1 $aCHAGAS, A. C. de S.
773 $tVeterinary Parasitology$gv. 328, june 2024, 110163.
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Embrapa Pecuária Sudeste (CPPSE) |
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